Selected Projects

Research directions that connect perturbation biology, AI virtual cells, computational chemistry, and phenotype-based therapeutic design.

AI-driven and Phenotype-based Drug Design

My earlier work focused on molecular generation, allosteric regulation, CRISPR-Cas9 conformational dynamics, and computational-experimental workflows for drug discovery. I am …

Computational Chemistry and CRISPR Allostery

I use molecular dynamics, docking, Markov state modeling, pathway analysis, and allosteric network analysis to study how molecular perturbations reshape protein conformational …

Perturbation Biology and AI Virtual Cells

I am interested in models that connect perturbations, cellular state transitions, and phenotype-level responses. Current directions include single-cell foundation model …